By "mainstream coverage," I refer to it in relation to the rest of game and anime coverage. After all, eroge and visual novel fans are a niche group within a niche group, a minority of "anime game" lovers, who in themselves are a minority of game lovers, who are a minority of the general public, and so on. By that logic, being featured in even a general game blog is worth noting.
The author in this case is Leigh Alexander, who in her semi-regular feature on Kotaku, highlighted Katawa Shoujo and its genesis, from idle sketches in a doujin artist's pad to the wilds of 4chan.
Worry not, however. Leigh is an experienced, thoughtful game critic and a veteran of the eroge scene, writing pieces about them for her "Aberrant Gamer" column in GameSetWatch. She gets why Kana: Little Sister is awesome, and highlights how Katawa Shoujo is similar in that respect. Check it out, read the whole thing, and it's worth the time you'll spend.
Unfortunately, as is usually the case whenever eroge, 4chan or even "anime games" in general are mentioned, much of the commentariat did not deign to read the whole thing, mostly going "ewww 4chan/Japanese/anime nerds are into cripples," and so on. Don't be like them, guys.
My only objection to the otherwise-excellent writeup is a side effect of the feature, in that Leigh has unfortunately - and perhaps indelibly - linked Four Leaf Studios (the developers) to the 4chan "community." That's a stigma no one wants.