Well ... I admit the whole phenomenon of marrying 2D characters gives me a chuckle. After all, I have an eternal thing for Kuroshitsuji's Sebastian, but when I realize the height of intimacy I can have with him is humping a dakimakura of him, the fantasy kind of fizzles for me. On the other hand, maybe some people have stronger imaginations than I do.
Anyway, we've heard tons about DS game Love Plus and all the crazy stuff it seems to make otaku do since it was released. Sankaku Complex reports that one man has taken it as far as to actually marry the game character Nene Anegasaki in a Guam church (see gallery for a photo of the church and the invitation). He also is planning a wedding reception back in Japan, where he apparently has invited media figures to attend.
NicoNicoDouga will be broadcasting the event live on November 22nd at 12:00 pm, in case you'd like to study it for your future marriage to Mio Akiyama.